EMBL-EBI Highlights report

Explore our latest achievements and how bioinformatics is enabling new solutions for disease research, AI, agri-tech and biodiversity.

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13 Nov 2025 - 13 Nov 2025

Chemicals in a biological context: metabolites, drugs, and beyond

Small molecules (or chemicals) play a crucial role in biological systems, acting as precursors to macromolecules, cells, and tissues. Beyond this, they are involved in cell signalling, regulation, energy consumption and production, and can be used therapeutically to treat diseases. Metabolites, a subset of small molecules, are the chemical intermediates and/or end products of metabolic processes.To understand the role of chemicals in a biological context, we can study how they bind to and impact the function of their macromolecular targets, such as DNA, RNA, and protein. We can also assess their broader functional impact on cells, tissues, blood, and other biofluids.This six-hour virtual workshop offers hands-on experience with EMBL-EBI tools and resources to explore the biological effects of small molecules. Using a case study, we will guide participants through workflows to investigate drug interactions with a protein target, as well as assess the downstream effects within a biological system. We will use ChEMBL to identify small molecule drugs and experimental data on their impact on targets, PDBe to evaluate target binding details, and MetaboLights to investigate the small molecule’s impact on biological systems.Virtual courseThis course will take place on Zoom. Trainers will be available to assist during practical sessions, answer questions, and provide further explanations during the Zoom.To join the course you will need to create an EMBL-EBI Training website account. 

Course

Virtual

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09 Feb 2026 - 13 Feb 2026

Introduction to RNA-seq and functional interpretation

Gain an introduction to the technology, data analysis, tools, and resources used in RNA sequencing and transcriptomics. The content will provide a broad overview of the subject area, and introduce participants to basic analysis of transcriptomics data using the command line. It will also highlight key public data repositories and methodologies that can be used to start the biological interpretation of expression data. Topics will be delivered using a mixture of lectures, practical exercises, and open discussions. Computational work during the course will use small, example data sets; and there will be no opportunity to analyse personal data. Virtual courseParticipants will learn via a mix of pre-recorded lectures, live presentations, and trainer Q&A sessions. Practical experience will be developed through group activities and trainer-led computational exercises. Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack.

Course

Virtual

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Careers at EMBL-EBI

Focus your energy and skills on something that really matters: using technology to contribute to discoveries that benefit humankind.

EMBL-EBI missions

We are EMBL-EBI: Our impact

The European Bioinformatics Institute (EMBL-EBI) is part of EMBL, Europe’s flagship laboratory for the life sciences. More about EMBL-EBI and our impact.

Data resources

Explore our open data resources to enrich your research. Browse data, perform analyses or share your own results.  

Research

Find out about our research groups, postdoctoral schemes and PhD Programme.

Training

Access a wealth of world-leading training in bioinformatics and scientific service provision, regardless of your career stage or sector.

Industry

Explore our knowledge-exchange Industry Programme and take part in translational partnerships and projects.

ELIXIR

We support, as an ELIXIR node, the coordination of biological data provision throughout Europe.

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EMBL’s European Bioinformatics Institute is one of the six sites of the European Molecular Biology Laboratory (EMBL). With over 20 member states and thousands of scientists and engineers working together, EMBL is a powerhouse of biological expertise.

EMBL is an intergovernmental organisation, headquartered in Heidelberg. It was founded in 1974 with the mission of promoting molecular biology research in Europe, training young scientists, and developing new technologies.

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